Aseptic Filling Machine Tray

Meeting Aseptic Requirements with Tray Filling Machines

Aseptic filling is a critical step in the manufacture of injectable drugs, as it takes place after each product and container has been sterilised. Any exposure to an uncontrolled environment can therefore compromise the safety of the final product. The aseptic tray filling machine allows sterile containers to be handled in an enclosure where particulate, microbiological and chemical contamination is strictly controlled.

This equipment is generally installed under an isolator or RABS (Restricted Access Barrier System) to create a physical barrier between the external environment and the filling area. It is designed to maintain ISO 5 conditions in the critical area, with laminar air flows, HEPA filtration and surfaces that are easy to decontaminate.

It should be noted that the process begins with the introduction of trays containing pre-sterilised vials or syringes. These trays are then automatically transported to the filling station. Peristaltic or piston pumps then ensure the liquid is dosed, while vision systems check that the containers are correctly positioned and the fill level is correct. The entire process is controlled by validated software, which guarantees repeatability, accuracy and traceability of operations.

What Technical Criteria should be Considered when Choosing an aAseptic Tray Filling Machine?

The choice of an aseptic tray filling machine depends on several technical parameters. These include, first and foremost, compatibility with the product to be filled, whether it is a clear liquid, a viscous product or a suspension. Above all, the dosing system must guarantee extreme precision with minimal product loss.

Flexibility is also an important consideration. A good machine should allow you to switch quickly from one bottle format to another or change trays without lengthy reconfiguration times. Modular components, quick-change tools (SMED) and standardised interfaces facilitate these operations.

The production environment must also be taken into account. The same applies to the integration of the machine into a complete line, compatibility with an isolator or RABS, connectivity with a SCADA or MES (Manufacturing Execution System), and the ability to generate GMP-compliant documentation. Finally, ease of cleaning (CIP) and sterilisation (SIP), mechanical robustness and the availability of spare parts are factors that should not be taken lightly in order to ensure reliable and sustainable production.

EREA Pharma, Specialist in Customised Aseptic Tray Filling Machines

Are you looking for a partner to design and manufacture customised aseptic tray filling machines? EREA Pharma can meet your needs. We have proven experience in sterile equipment, enabling us to design solutions that are fully tailored to each customer’s specific requirements, from prototyping to cleanroom integration.

Our various machines are designed to integrate easily into complex aseptic environments, under isolators or RABS, in compliance with current international standards. Each project is treated individually, whether it involves filling vials, cartridges or syringes, with variable speeds and dosing systems adjusted to the type of liquid to be handled.

What’s more, our machines incorporate the latest motorisation, control, detection and traceability technologies. We also support our customers throughout all qualification phases (FAT, SAT, IQ/OQ), ensuring a high level of regulatory compliance. Thanks to our expertise and innovation-focused approach, we offer high-performance, scalable and safe aseptic tray filling machines that meet the current and future requirements of the pharmaceutical industry.

Are you considering adopting our machines in your business? Get a quote quickly by contacting us.