Radiopharmaceutical Shielded Vial Filling Line (Injectable Radioisotopes)

Characteristics of Radiopharmaceutical Vials and Associated Uses

A container adapted to injectable radioisotopes

Shielded radiopharmaceutical vials are designed to hold sensitive and radioactive injectable products. They are made of Type I glass, the reference material for critical formulations, and are compatible with external shielding necessary for protecting operators and the environment. The usual formats range from two to fifteen millilitres, aligned with common radioisotope injection volumes.

A closure system compliant with nuclear medicine requirements

Each vial is sealed with a stopper and crimp cap, with the option of integrating sampling ports suitable for hot-cell handling. This closure system ensures product sterility while allowing the operations required for dosing, sampling and administration.

Applications dedicated to radiopharmaceuticals

These containers are used for radioactive injectables such as FDG or MIBG. Their shieldable design, combined with standardised interfaces, enables seamless integration into production, handling and distribution environments used in nuclear medicine.

Specific constraints to consider

Radioisotopes undergo rapid decay, which requires strict time control at every stage of the process. The vial must allow fast, precise and secure manipulation inside a sterile hot-cell environment, where operator protection and container reliability are essential.

The Radiopharmaceutical Vial Filling Line According to EREA

Mastery of sterile filling in hot-cell environments

We design filling lines capable of handling the constraints associated with radiopharmaceutical products. The process includes vial preparation, sterile dosing, crimp sealing and control of critical parameters, all within an environment designed for radiological protection and microbiological control.

A solution designed for radioisotope decay constraints

Our filling lines are configured to meet the time-sensitive requirements of radioisotope decay. Every filling sequence is optimised to ensure speed, accuracy and continuity, preserving product activity while maintaining operator safety.

A customised filling line for nuclear medicine

We develop fully personalised equipment tailored to each production environment, vial formats, shielding requirements and sterility constraints. Our teams support every stage of the project, from initial study to commissioning, including qualification, validation and process optimisation.
This approach ensures reproducible, secure filling adapted to the specific conditions of nuclear medicine, while guaranteeing safe storage, handling and injection of radioisotopes.