Multi-chamber bag filling line (nutrients, RTU antibiotics)
The multi-chamber bag filling line (for nutrients and RTU antibiotics) is based above all on a specific type of container. The multi-chamber bag belongs to the family of infusion bags. It provides a flexible, sterile, and ready-to-use solution for sensitive intravenous preparations. The bag features several compartments separated by peelable seals, ensuring controlled mixing at the time of use. Its design focuses on safety, ease of activation, and formulation stability.

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Sterile multi-chamber bag solutions
These bags use robust materials such as PP, PE, or EVA. These polymers offer excellent compatibility with nutritional solutions and RTU antibiotics. Volumes range from 50 to 1000 mL to meet diverse clinical requirements. The chambers are separated by peelable seals, enabling rapid mixing through simple activation of the internal break point.
Thus, the multi-chamber configuration guarantees sterile reconstitution immediately before administration and reduces risks associated with repeated handling. This approach integrates seamlessly with EREA Pharma’s aseptic filling machines, specifically designed to handle flexible and complex formats.
Key container features:
- Materials: PP, PE, EVA
- Volumes: 50–1000 mL
- Peelable seals for secure mixing
Clinical applications and fields of use
These bags are widely used in clinical nutrition, RTU antibiotic preparation, and hospital sterile compounding units. They meet the requirements of medical environments where every step must remain controlled.
Multi-chamber bags ensure reliable mixing and reduce cross-contamination. This configuration is ideal for sensitive preparations requiring immediate reconstitution. They are also commonly used in infusion services where patient safety is a priority. In addition, the multi-chamber system simplifies internal logistics by reducing stocks of pre-mixed preparations while improving therapeutic flexibility.
Their main advantage lies in secure mixing, while their only limitation concerns the potential risk of incorrect activation. However, this risk remains low when the bag is used within a controlled workflow.
Aseptic filling line for multi-chamber bags
EREA Pharma’s automatic filling line provides a reliable process for multi-chamber bag filling. It ensures precise volume control and homogeneous distribution across each compartment. All movements are fully automated to guarantee a stable and consistent process flow.
This multi-chamber bag filling line (for nutrients and RTU antibiotics) offers accuracy, safety, and repeatability. It maintains strict aseptic conditions throughout the entire cycle. The system automatically integrates filling, inspection, sealing, and quality control stages. Thanks to this high level of automation, the bags consistently meet international pharmaceutical standards.
Multi-chamber bags, combined with a suitable aseptic filling line, offer a reliable solution for sensitive preparations. To explore a customised configuration or receive a detailed technical assessment, a professional consultation will allow for an in-depth review of your project.
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